Human-derived PD-1 protein usually exists in a monomeric form. It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) , which can play an important role in peripheral tolerance and autoimmune diseases. PD-1 can be used as a cell surface inhibitory receptor to participate in the regulation of T cell immune tolerance. After binding to the ligand, it can inhibit T cell effects at the antigen-specific level. This product can be used to overexpress PD-1Flow cytometric detection of recombinant cell lines and activity detection of recombinant proteins.

Product name: PD1 recombinant antibody

Reactivity: human

Subclass: human IgG4

Concentration : 1μg/μL

Analysis instrument: flow cytometer

Purification method: affinity chromatography

Storage system: PBS, pH 7.4, 20% glycerol

Storage conditions: -20°C refrigerator, avoid repeated freezing and thawing

Illustration: Lane M on the left is: protein MW marker, Lane 1 is: 10ug PD1 antibody

The picture on the right shows the FACS detection of PD-1 monoclonal antibody binding to CHO-K1-PD1.

Reference materials:

https://www.news-medical.net/health/Programmed-Cell-Death-Protein-1-(PD1).aspx