Protein Expression Services: Empowering Global Biopharmaceutical Development

International Standards · Efficient Delivery · Full Compliance

Technical Capabilities

Precision for Complex Requirements

  • 500+ Successful Cases: Covering antibodies, enzymes, membrane proteins, and multi-subunit complexes, with validated data on expression yield, purity (e.g., SEC-HPLC ≥95%), and activity (SPR/ELISA verification).

  • Comprehensive Expression Systems: Integrated E. coli and Pichia pastoris platforms enable rapid screening, high-yield production, and scalable fermentation from flask-scale small batches to 300L fermenters, supporting R&D optimization to pilot-scale production.

  • Breakthrough Technologies: Expertise in stabilizing cytotoxic proteins and assembling multi-subunit complexes is combined with precision modification technologies, including site-directed glycosylation and phosphorylation optimization, to achieve tailored functional outcomes.

Quality Control

Traceable Data, Global Compliance

  • Rigorous Testing Protocols: Rigorous quality assessment integrates orthogonal methodologies, including SDS-PAGE and HPLC (SEC/IEX) for purity profiling, SPR and ELISA coupled with functional cell-based assays for activity validation

  • Batch Consistency: Full process parameter documentation, endotoxin ≤1 EU/μg (LAL method).

Project Timeline

Flexibility for R&D Agility

  • Customized Development Paths: Tailored strategies for diverse goals (structural analysis, functional validation, preclinical studies).

  • Phased Deliverables: Stage-based milestones (e.g., gene synthesis → flask-scale expression → process optimization).

  • Priority Resource Allocation: Expedited workflows for urgent projects with dedicated expert support.

  • Seamless Scale-Up: Smooth transition from flask-scale to 300L fermenters, ensuring R&D-to-production continuity.

Intellectual Property

Secure & Compliant

  • Data Security: Client gene sequences are secured within isolated server environments utilizing end-to-end encryption for all data transmission and storage phases

  • Patented Technology: Internationally licensed Pichia pastoris expression system

  • Regulatory Compliance: Operations aligned with China’s Biosecurity Law and industry ethics standards.

Global Collaboration

Cross-Border Expertise

  • Logistics Assurance: End-to-end cryogenic logistics (-80°C) with real-time thermal telemetry and validated chain of custody documentation, coupled with regulatory navigation for China Customs export permits and on-demand third-party audit protocols to enforce operational transparency.

  • Third-Party Audits: Available upon client request to ensure transparency.

Long-Term Partnership

End-to-End Support

  • Integrated Services: Protein expression → stable cell line development → process scale-up.

  • Risk Mitigation: 48-hour expert response for technical challenges (e.g., host switching/vector optimization).

  • Flexible Engagement Models: Fee-for-Service (FFS) / Co-Development (risk/revenue sharing).