Technical Capabilities
Precision for Complex Requirements
500+ Successful Cases: Covering antibodies, enzymes, membrane proteins, and multi-subunit complexes, with validated data on expression yield, purity (e.g., SEC-HPLC ≥95%), and activity (SPR/ELISA verification).
Comprehensive Expression Systems: Integrated E. coli and Pichia pastoris platforms enable rapid screening, high-yield production, and scalable fermentation from flask-scale small batches to 300L fermenters, supporting R&D optimization to pilot-scale production.
Breakthrough Technologies: Expertise in stabilizing cytotoxic proteins and assembling multi-subunit complexes is combined with precision modification technologies, including site-directed glycosylation and phosphorylation optimization, to achieve tailored functional outcomes.
Quality Control
Traceable Data, Global Compliance
Rigorous Testing Protocols: Rigorous quality assessment integrates orthogonal methodologies, including SDS-PAGE and HPLC (SEC/IEX) for purity profiling, SPR and ELISA coupled with functional cell-based assays for activity validation
Batch Consistency: Full process parameter documentation, endotoxin ≤1 EU/μg (LAL method).
Project Timeline
Flexibility for R&D Agility
Customized Development Paths: Tailored strategies for diverse goals (structural analysis, functional validation, preclinical studies).
Phased Deliverables: Stage-based milestones (e.g., gene synthesis → flask-scale expression → process optimization).
Priority Resource Allocation: Expedited workflows for urgent projects with dedicated expert support.
Seamless Scale-Up: Smooth transition from flask-scale to 300L fermenters, ensuring R&D-to-production continuity.
Intellectual Property
Secure & Compliant
Data Security: Client gene sequences are secured within isolated server environments utilizing end-to-end encryption for all data transmission and storage phases
Patented Technology: Internationally licensed Pichia pastoris expression system
Regulatory Compliance: Operations aligned with China’s Biosecurity Law and industry ethics standards.
Global Collaboration
Cross-Border Expertise
Logistics Assurance: End-to-end cryogenic logistics (-80°C) with real-time thermal telemetry and validated chain of custody documentation, coupled with regulatory navigation for China Customs export permits and on-demand third-party audit protocols to enforce operational transparency.
Third-Party Audits: Available upon client request to ensure transparency.
Long-Term Partnership
End-to-End Support
Integrated Services: Protein expression → stable cell line development → process scale-up.
Risk Mitigation: 48-hour expert response for technical challenges (e.g., host switching/vector optimization).
Flexible Engagement Models: Fee-for-Service (FFS) / Co-Development (risk/revenue sharing).
