Pharmacodynamic evaluation

ADCC activity detection

In order to solve the common problems in the traditional ADCC test, we used the luciferase reporter gene detection system as the platform to construct stable transfection of CD16 receptor and NFAT (Nuclear Factor of Activated T -cells) Jurkat-NFAT-Luc-CD16 cell line of the original reaction.

Pharmacodynamic evaluation of TGF-β neutralizing antibody

icartab has constructed a 293F-TGF-β-Luc cell line stably transfected with TGF-β, which can provide the process of antibody discovery, signal pathway blockade and cell function detection, and is a preclinical in vitro study of the target of TGF-β provide the solution.

PD1/PDL1 reporter gene experiment service

PD-1, also known as programmed cell death protein 1 or CD279 (cluster of differentiation 279), is a cell surface receptor, a member of the immunoglobulin superfamily, expressed on T cells and B cells.