Recombinant human PDL1 protein (PDL1-FC)
|IRP002A||Recombinant human PDL1 protein|
|NP_054862.1/（19-238AA）||C-terminal Human-Fc Tag|
Programmed cell death 1 ligand 1 (PD-L1) is a member of the B7 superfamily. Highly expressed PD-L1 can inhibit T cells by inhibiting cell signaling pathways such as RAS and PI3K/AKT. Proliferation or induction of CTL apoptosis; down-regulation of mTOR, AKT, S6 and ERK2 phosphorylation and up-regulation of PTEN can promote the production of induced Tregs, and then inhibit the activity of effector T cells. This product is a PD-L1 (19-238AA)-FC recombinant protein, which can be used for monoclonal antibody screening or antibody function verification.
Recombinant human PD1 protein (PD1-FC)
PD-1 (Programmed cell death protein 1), also known as PDCD1, is an important immunosuppressive transmembrane protein expressed on the surface of T cells.
|CAT#||Protein Name||Expression region||Tag position||Restriction sites|
|IRP002A||Recombinant human PDL1 protein||NP_054862.1/（19-238AA）||C-terminal Human-Fc Tag||无|